A fun little project. We were curious if you could prep a single sample using both 10X Genomics Xenium V1 probes and Prime probes – allowing users to profile 480 genes at high sensitivity and 5,000 genes at lower sensitivity inline.
www.biorxiv.org/content/10.6...
Spatial transcriptomics faces a trade-off between the number of genes assayed and depth of per-gene sensitivity. We developed a 'dual chemistry' method that combines the high sensitivity of a 10X Geno...