Sharing our latest work from the Hernando lab in
@aacrjournals.bsky.social Cancer Discovery.
Thanks to the collaborative effort between #nyulangone and internation institutions we show how melanoma cells can evade the immune system by activating the transcription factor HOXD13.
aacrjournals.org
Abstract. Ultraviolet (UV)-induced DNA mutations generate genetic drivers of cutaneous melanoma and numerous neoantigens that can trigger anti-tumor immunity. Melanoma cells must therefore rapidly eva...