Another great preprint out from the Hernando lab, lead by Maria Gomez and Allie Kartz. Did you know that melanoma brain metastasis upregulate the carnosine dipeptidase CNDP1 through MITF to prevent intracellular copper accumulation?
www.biorxiv.org/content/10.1...
Brain metastatic cells undergo metabolic adaptations, such as increased reliance on oxidative phosphorylation. Integrating proteomic and transcriptomic profiling of patient samples revealed a consiste...
