This is seminal work by an outstanding team performing heroic studies that builds a translational bridge that will invariably in treating depression.
You could never simulate anything this complex on a chip and it’s foolish to think otherwise.
Vinny Costa
A few years back we started a collaboration to try to work out the mechanisms engaged by DBS for depression. Published today we found that it changes functional networks (expected) but also remodels specific white matter tracts (unexpected). Read more here: www.nature.com/articles/s41...
In a nonhuman primate model, Fujimoto et al. show that deep brain stimulation promotes white matter remodeling and reorganizes brain-wide functional networks, detailing a mechanism through which this ...
