But it turns out the ability to induce a strong immune response is separate from these effects and we have had a bunch of recent work showing that it is possible to simultaneously make mRNA vaccines more effective AND make them a much more tolerable experience for people:
rdcu.be/fosUY
Nature Materials - Lipid nanoparticles incorporating a crosslinked ionizable lipid are shown to promote efficient endosomal escape of antigen mRNA and glycolysis stimulation in dendritic cells, to...