YSBL, Department of Chemistry, University of York, UK. I make, modify and fix stuff. Acta Cryst F main editor with Mark and Cristy. CCP4wg2 chair with Arnaud. Analyse glycan structures with Privateer: https://privateer.york.ac.uk #RealTimeChem [He/Him]
Jon Agirre
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Please watch, like and subscribe (if you like it, of course), and leave us some comments! What would you like to see in these interviews? Would you prefer shorter/longer interviews? Would you like to be considered for an interview on your next @actacrystf.iucr.org article? Let us have your thoughts!
In our latest episode of Interviews With Authors, we discussed PentatricoPeptide Repeat (PPR) proteins, their roles in RNA binding, use in protein design and other things, and I'd like to share some highlights.
What are PPR proteins and why do they matter, you may ask? Anuradha has the answers:
In our latest episode of Interviews With Authors, we discussed PentatricoPeptide Repeat (PPR) proteins, their roles in RNA binding, use in protein design and other things, and I'd like to share some highlights.
What are PPR proteins and why do they matter, you may ask? Anuradha has the answers:
It was lovely to chat with Anu and @charliebondxray.bsky.social about PPR proteins, their RNA binding modes and awesome modularity. Please watch, give the IUCr a thumbs up, and add some comments when you have a minute! What would you like to see in these interviews?
Unrelated to PPRs, there was an interesting question formulated by @markvanraaij.eurosky.social about the challenges and opportunities of working in Perth, said the be the most isolated major city.
www.youtube.com/watch?v=nYcF...
Challenges in integrating AlphaFold predictions and protein dynamics into PPR design workflows, given that their plasticity?
www.youtube.com/watch?v=nYcF...
About those conformational changes in PPR proteins — is structural plasticity required for binding?
www.youtube.com/watch?v=nYcF...
What are the most popular modifications to PPRs that have been introduced by the community?
www.youtube.com/watch?v=nYcF...
Reconciling non-canonical binding modes in PPR design — are we reaching the limits of a simple recognition code?
www.youtube.com/watch?v=nYcF...
Ikuya Kurauchi et al.: Crystal structure of endo-β-N-acetylglucosaminidase HSα #EndoNAcetylglucosaminidases #GH85 #ComplexNGlycans ... #IUCr https://journals.iucr.org/paper?S2053230X26001214
YouTube video by International Union of Crystallography