#3Dgenome, #3R, #chromatin, #synbio, #microbiome... Opinions are my own.
Romain Koszul
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On this day, in 1961, two articles appeared in Nature announcing the isolation of messenger RNA (mRNA)
www.cell.com/current-biol...
www.cell.com
Cobb looks back at the complicated series events that led to the discovery of messenger
RNA, highlighting the often difficult problem of attributing credit for scientific
advances.
This one means a lot. Our paper, “Large extrachromosomal replicons are widespread across bacterial lineages and show coordinated replication termination and spatial coupling with the chromosome,” is out!
doi.org/10.1038/s414...
Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org
Big change for researchers with disabilities who seek a faculty position in France. Positions are now open to any lab in the country and there are 2 positions for biology labs.
carrieres.cnrs.fr/actualites/r...
Nerd alert: 10 000 bandes pirates de concert - enregistrées sur plus de 30 ans - rendues disponibles à tout le monde
www.dexerto.com/entertainmen...
Bacterial genomes often include extrachromosomal replicons, ranging from small plasmids to chromosome-scale replicons. Here, Czarnecki et al. analyse more than 40,000 complete bacterial genomes and sh...
A quick notice: the Hi-C scaffolder InstaGRAAL is available on PyPI, with an -endtoend mode that should facilitate homemade scaffolding project.
"pip install instagraal" and info here:
github.com/koszullab/in...
(non contractual movie since we removed the openGL visual long ago :-)
Les candidats retenus signent un contrat d’un an, qui peut être renouvelé pour une durée n’excédant pas celle fixée initialement. Pendant cette période, ils bénéficient des mêmes conditions de travail, droits et avantages que les chercheurs stagiaires de la fonction publique.
Happy to share our review of the past, recent, and future applications of synthetic genomics in studying the 3D functional organization of chromosomes, a set of approaches that are gaining momentum!
www.sciencedirect.com/science/arti...
sPYce is now published in Nature Ecology and Evolution!
sPYce is a method to integrate single-cell regulatory data across species, without requiring whole-genome alignments between species.
More below ⬇️
www.nature.com/articles/s41...
Romain Koszul
The role of genome 3D organization for fundamental chromatin processes, such as long-range promoter-activator regulatory interactions, remains ambiguo…
This paper presents sPYce, a method that integrates single-nucleus ATAC-seq data across species, allowing for comparison of gene regulatory evolution across species.
www.nature.com
Jean Léon Maître
Pierre Bataille
www.lemonde.fr
Moisissures dans les collections, bibliothèque inondée, fissures dans les murs… Alors que l’établissement célèbre ses 400 ans, fort d’une importante fréquentation et d’une renommée scientifique intern...
