Alternative organelle targeting of OPA1 mediates fatty acid release from lipid droplets https://www.biorxiv.org/content/10.64898/2026.05.07.723579v1
🚨Excited to announce a new preprint from our lab, where we describe an ancient metabolic axis that controls mitochondrial genome copy number; a mechanism we uncovered in human cells that stretches through evolution to control mtDNA in flies, yeast and even plants!
www.nature.com/articles/s41...
#Mitochondria serve as a holdout compartment for aggregation-prone proteins hindering efficient degradation
www.nature.com/articles/s41...