back to back with related study from Jan-Michael Peters' group
PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes
www.cell.com/molecular-ce...
PDS5 proteins regulate genome organization by halting cohesin-mediated loop extrusion.
Wutz et al. show that PDS5 promotes NIPBL dissociation from cohesin, enabling CTCF
boundary formation and proper ...