Freitas et al. report that coaggregation of stem cell–derived-β cells with proregenerative macrophages results in improved β cell maturity, function, metabolic activity, and accelerated normoglycemia posttransplantation in immune-deficient, diabetic mice. 🧪
www.science.org/doi/10.1126/...
SC-β and SC-MReg coaggregates have improved insulin secretion, metabolic function, and reverse hyperglycemia in diabetic mice.
