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Supported by NIH, the NIH Pragmatic Trials Collaboratory is advancing the design, conduct, and dissemination of pragmatic clinical trials. Learn more at rethinkingclinicaltrials.org.
NIH Pragmatic Trials Collaboratory









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📣 In this week's PCT Grand Rounds, Jamie Forrest of @science.ubc.ca will present “The REVIVE-TOGETHER Trial: Findings From an Evaluation of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID.” Join us! 🔗 duke.is/pctnews20260...
📣 In this week's PCT Grand Rounds, Alison Huang and Derek Angus of JAMA+ Trials will present “Bringing Context and Clarity to Clinical Trial Research for Clinician and Public Health Audiences.” Join us! 🔗 duke.is/pctnews20260...
🎙️ In a new episode of the NIH Collaboratory Podcast, Roy Perlis of @harvardmed.bsky.social and JAMA+ AI discusses the impact of AI on the scientific publishing industry as well as the opportunities and risks that lie ahead. 🔗 Listen and subscribe: duke.is/pctpod
The LungSMART team conducted a bilingual formative evaluation to improve the study’s digital health content for patients in community health centers in Utah. A full pragmatic trial will test strategies to promote lung cancer screening. Learn more ➡️ duke.is/pctnews20260...
🛠️ The study design paper has been published for AIM-CP, an NIH Collaboratory Trial. Learn about this innovative pragmatic trial testing the use of a nurse care management program to improve access to nonpharmacological treatments for chronic pain in rural populations. duke.is/pctnews20260...
We recently spoke with Lynn DeBar and Nicole Cook, co–principal investigators for the CARNATION trial, about enabling community health centers to use the EHR for coordinating primary care–based pain management in their NINDS-supported study. duke.is/pctnews20260...
Now's the time to submit your presentation proposals to @academyhealth.bsky.social for the 19th Annual Conference on the Science of Dissemination and Implementation in Health. duke.is/pctnews20260...
Feasibility assessment in pragmatic trials is about more than reaching milestones or completing a checklist. It should be a discovery process in which investigators generate hypotheses and collect data. Check out our interview with Angelo Volandes and Sebastian Tong. ➡️ duke.is/pctnews20260...
We recently spoke with Kathleen Sluka, co–principal investigator for the FM-TIPS trial, about the results of the study and lessons for future pragmatic research. duke.is/pctnews20260...
📣 In this week's PCT Grand Rounds, Thomas J. Stopka of @tuftsmedschool.bsky.social will present “Mobile Telemedicine for Treating Chronic Hepatitis C Among Rural People Who Inject Drugs: A Randomized Clinical Trial.” Join us! 🔗 duke.is/ptcnews20260...
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NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
NIH Pragmatic Trials Collaboratory
The study design paper for AIM-CP has been published online in PLoS One. Congratulations to the study team on reaching this important milestone for all NIH Collaboratory Trials! The AIM-CP […]
duke.is
The planning phase of a pragmatic clinical trial is a critical time when research teams can hone their research questions, build relationships with healthcare system and community partners, and test [...
duke.is
May 28, 2026: Study Design Paper Published for AIM-CP - Rethinking Clinical Trials
June 4, 2026: Feasibility Assessment in Pragmatic Trials: An Interview With Angelo Volandes and Sebastian Tong - Rethinking Clinical Trials
AcademyHealth issued a call for presentations for its 19th Annual Conference on the Science of Dissemination and Implementation (D&I) in Health. The theme of this year’s conference is “Elevating the [...
duke.is
June 8, 2026: AcademyHealth Issues Call for Presentations for 2026 D&I Conference - Rethinking Clinical Trials
CARNATION, an NIH Collaboratory Trial, will test an implementation support intervention designed to enable community health centers to use electronic health records for coordinating primary care–based...
duke.is
June 9, 2026: Updates From the CARNATION Trial: An Interview With Lynn DeBar and Nicole Cook - Rethinking Clinical Trials
FM-TIPS, an NIH Collaboratory Trial, examined whether the addition of transcutaneous electrical nerve stimulation (TENS) to routine outpatient physical therapy improves pain compared with physical the...
duke.is
June 2, 2026: Highlights From the FM-TIPS Trial: An Interview With Kathleen Sluka - Rethinking Clinical Trials