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Excited to see our manuscript out @natcomms.nature.com pubmed.ncbi.nlm.nih.gov/40721431/. We identified that the 18S rRNA methylase DIMT-1 regulates lifespan by functioning in the germline after midlife. 1/8
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Specialized ribosomes help determine which proteins are synthesized, however, the influence of age on ribosome heterogeneity and whether dysregulation of this process drives organismal aging is unknow...
pubmed.ncbi.nlm.nih.gov
The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life - PubMed