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Using frog metamorphosis, we show that spinal cord cell types diversify as locomotion shifts from swimming to walking, revealing a conserved blueprint for interneuron circuits across tetrapods. πŸŸβ†’πŸΈβ†’πŸ­ πŸ“„ www.cell.com/cell-reports...
Frog metamorphosis reveals how spinal circuits adapt to new motor demands. Vijatovic et al. demonstrate that the shift from tail- to limb-based locomotion coincides with expansion and diversification ...
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Multifold increase in spinal inhibitory cell types with emergence of limb movement
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David Vijatovic, PhD