Big news for correlative cryogenic SMLM/ET! With my colleague Soheil, we (Mahamid and @jonasries.bsky.social labs) indicate lamella-specific illumination can allow 500-1500x higher laser intensities, opening massive new possibilities for correlative imaging #teamtomo
www.biorxiv.org/content/10.6...
Video
joe dobbs
First steps into cryo-lamella imaging by cryo-secondary ion mass spectrometry using helium and neon ion microscopy! We look forward to continuing with correlative cryo-EM-SIMS. Great work: Antje Biesemeier and colleagues - Luxembourg Institute of Science and Technology. pubs.acs.org/doi/10.1021/...
Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.
Chlanda lab
Congratulations to Dao Thi lab @daothilab.bsky.social
and collaborators! Beautiful work! @ciid-heidelberg.bsky.social
Happy to see the preprint of our VULCROM setup online! Thanks to our amazing collaborators we've managed to get some pretty cool cryo-CLEM images by combining cryo super-resolution and cryo-ET: doi.org/10.64898/202...
Join us at the 24th Workshop Cell Biology of Viral Infections @gesvirologie.bsky.social, Schƶntal Monastery, 28ā30.10.2026 cellviro.g-f-v.org
āCellular Routes and Roadblocks in Viral Genome Traffickingā
Speakers:
@beatesodeiklab.bsky.social · Alba Diz-Muñoz · @carogoujon.bsky.social · Redmond Smyth
Jason McLellan
Chlanda lab
Preprint š§µ!
Iām really excited to introduce BIGSMALL, an interleaved multi-magnification cryo-ET scheme bridging molecular and cellular scales in a single acquisition!
BIGSMALL = šroad šnformation šathering štrategy by šultiscale šcquisition of lamešša
www.biorxiv.org/content/10.6... (1/6)
Chlanda lab
KaufmannLab
Excited to advertise a fully funded PhD with @socialinfluenza.bsky.social investigating how influenza virus evolution differs between different avian hosts (and how this impacts pandemic potential). Joint between @pirbrightinst.bsky.social + @cvrinfo.bsky.social
www.findaphd.com/phds/project...
PhD Project - FULLY FUNDED PhD - Visualising avian influenza virus tropism and co-infection in avian hosts at University of Glasgow, listed on FindAPhD.com
www.findaphd.com
Meet our new #AllianceFellow Jack Whitehead!
The short interview about his work in the @chlandalab.bsky.social and Mahamid lab at @embl.org can be found on our LinkedIn account.
@jackwh18.bsky.social
We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses donāt just borrow a helper virus. They can travel inside it.
A literal Trojan Horse āvirus-in-a-virusā route into cells. 𤯠Kudos to 1st author @viroscope.bsky.social and co-authors !
Multimodal helium ion microscopy (HIM) and secondary ion mass spectrometry (SIMS) provide in situ spatial imaging and chemical analysis at nanoscale resolution. Operation at cryogenic temperatures is ...
Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to exprā¦
Health + Life Science Alliance Heidelberg Mannheim
Karim Majzoub
š¬ New insights into hepatitis E virus replication š¬
Study reveals HEV replication occurs in proliferative cells within the intestinal crypt.
Read more: www.science.org/doi/10.1126/...
#HEV #HepatitisE #Research #Virology #RUB #HepEHub
Meet our new Alliance Fellow Jack Whitehead!
Q: Could you tell us a bit about the work you do? Which field do you work in and who are your PIs?
A: I am a structural biologist, and my work looks at th...
www.linkedin.com
Virologie Bochum
Hepatitis E virus infection of the self-renewing intestinal crypt reveals a previously unknownmechanism of viral persistence.