This Plasmid Project was directly inspired by the results on multilevel selection that Dan introduced me to! In this thread he explains some fundamental theoretical results that were so influential to me as a Scientist. Looking forward to more Math-driven experiments!!! Thanks Dan!
Fernando Rossine
I'm really excited to see this paper by @fernpizza.bsky.social, @baym.lol, et al. This is a great model system for studying multilevel selection, and the experimental work builds nicely on cross-scale theoretical modeling approaches that I've enjoyed learning about over the past few years. 🧵
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
