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Forschende der @unigreifswald.bsky.social haben einen neuen Mechanismus entdeckt, mit dem Bakterien wie Bacillus subtilis die Produktion des zentralen Stoffwechselmoleküls Acetyl-Coenzym A (Acetyl-CoA) regulieren können. doi.org/10.1038/s414...
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AcuB senses cellular energy charge to coordinate acetyl-CoA synthesis in bacteria - Nature Communications
Bacteria adjust their metabolism to the cellular energy state. Here, authors identify a layer of regulation of AMP-forming acetyl-CoA synthetase AcsA activity by AcuB acting as energy sensor inhibitin...
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