Head of Molecular Microbiology @johninnescentre.bsky.social. Streptomyces natural products. Drummer, husband, dad, Norwich City ST holder.
www.jic.ac.uk/people/matt-hutchings
Streptomyces strains & resources @ http://streptomyces.org.uk
Matt Hutchings
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Excited to share this paper from @yiechanglin.bsky.social showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. 🎥🌟 #MDsimulations #StructuralBiology doi.org/10.1016/j.bp...
Video
Good to see this in the @microbiologysociety.org special collection, Advances in the Biology of Actinomycetes.
OrrA directly controls WblA, a key regulator of sporulation and antibiotic production. A great team effort @johninnescentre.bsky.social
www.microbiologyresearch.org/content/jour...
Good to see this in the @microbiologysociety.org special collection, Advances in the Biology of Actinomycetes.
OrrA directly controls WblA, a key regulator of sporulation and antibiotic production. A great team effort @johninnescentre.bsky.social
www.microbiologyresearch.org/content/jour...
A couple of colourful and obliging Sicilian Wall Lizard (Podarcis waglerianus) - endemic to Sicily. Many thanks
@paulhoskisson.bsky.social for identification, via @matthutchings.bsky.social
“look up at the stars and not down at your feet. Try to make sense of what you see…. Be curious. And however difficult life may seem, there is always something you can do and succeed at. It matters that you don’t just give up.”
www.theguardian.com/science/2026...
Our latest paper ‘Ecological context for bacterial natural products’ is now out in the Royal Society of Chemistry @natprodreports.rsc.org
International effort with @jonathanparra.bsky.social, Marla I Macias-Contreras & Dulce Guillen Matus #puravida #naturalproducts
pubs.rsc.org/en/Content/A...
Visit our website to find out more and discover whether you could be one of three lucky schools who could join our mission!
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Streptomyces bacteria have complex life cycles involving hyphal growth, sporulation and the production of diverse specialised metabolites, including antibiotics. In this study, we investigated the rol...
Streptomyces bacteria have complex life cycles involving hyphal growth, sporulation and the production of diverse specialised metabolites, including antibiotics. In this study, we investigated the rol...
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Exclusive: New biography uncovers Frank Hawking’s papers in which he lamented that his son had ‘little initiative’
Really pleased to finally see this out! More insights into the global regulator MtrA and how it helps S. ven sense and respond to its environment.
Matt Hutchings
Another paper out in the @microbiologysociety.org special issue on Advances in the biology of Actinomycetes! Congratulations to everyone involved @matthutchings.bsky.social @barriewilks.bsky.social @johninnescentre.bsky.social
www.microbiologyresearch.org/content/jour...
Covering: This review covers literature from 2015 to present.It is widely recognised that there is a significant gap between bacterial natural product potential and detected/described products. As suc...
Streptomyces bacteria have complex life cycles involving hyphal growth, sporulation and the production of diverse specialised metabolites, including antibiotics. In this study, we investigated the rol...
Great to see this published in the @microbiologysociety.org collection on Actinomycetes
Conserved regulator MtrA directly activates ectoine biosynthesis and expression of BldM and WhiI to trigger sporulation in response to hyperosmotic stress
www.microbiologyresearch.org/content/jour...
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The MtrAB two-component system is a master regulator of antibiotic biosynthesis in Streptomyces species. MtrA is also required for sporulation under certain growth conditions, which means that on some...
