All about neuronal activity: development, visual cortex, neuromodulation, interneurons, patch-clamp, and in vivo calcium imaging.
Neuroscience blog: https://spikesandbursts.wordpress.com/
David
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Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target: doi.org/10.1016/j.ne...
EPAC2 (exchange protein directly activated by cAMP 2) antagonist rescued circuit and behavioral phenotypes in Fmr1 KO mice.
Nature research paper: Feature-specific threat coding in lateral septum guides defensive action
go.nature.com/4uv9qps
Thalamic activity regulates interneuron density in the developing visual thalamus
www.jneurosci.org/content/earl...
David
David
Nature
The populations of CRHR2-expressing neurons in the lateral septum of mice involved in threat-related behaviour in response to environmental challenges are defined.
Neural activity is a fundamental driver of early circuit assembly, yet how it shapes the distribution of inhibitory neurons across sensory networks remains poorly understood. Establishing an appropria...
