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Out today in @cp-molcell.bsky.social! We show that proximal polyadenylation site (pPAS) within MRE11 sustains its transcription through promoter–PAS chromatin looping. Congratulations to first author Kaimeng Huang, all co-authors and collaborators. www.sciencedirect.com/science/arti...
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Alternative polyadenylation (APA) generates transcript isoforms with variable 3′ untranslated regions (UTR) lengths, yet its role in DNA damage respon…
www.sciencedirect.com
MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability
Chowdhury Lab