Interesting paper from Virginie Ropars and collegues about the architecture of WRN and KU interaction. Interestingly, WRN binds on the internal (end-distal) side of KU. Thanks for this interesting collaboration! @pietropichierri.bsky.social
www.nature.com/articles/s41...
The WRN helicase helps to protect stalled DNA replication forks during replication stress, but its activation mechanism remains unclear. Here, the authors demonstrate that Ku binds and stimulates WRN ...