Saturated long-chain fatty acids suppress ILC3 function and increase gut inflammation, while unsaturated ones sustain IL-22 production through lipid droplets formation
Excited to see our work published on @cp-immunity.bsky.social.
Also shared by a nice commentary. really like the last sentence:
“Not all fuel nourishes; some, once ignited, may burn beyond control.”
Long-term consumption of diets high in fats has detrimental impacts on the immune
system, but the window necessary for initiating these effects is unclear. In this
issue of Immunity, Xiong et al. demo...
www.cell.com
Le Xiong
🎓 PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
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Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination.
Published in @jem.org
www.wehi.edu.au/news/vaccine...
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health.
Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint #chronicinflammation at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
#WeekendRead! #NotAllFatIsEqual! @lexiong.bsky.social Seillet &co show @cp-immunity.bsky.social that #diet saturated fatty acids rapidly impair (while unsaturated fatty acids favor via lipid droplets) IL22 production by ILC3 supporting dysbiosis & gut permeability, exacerbating inflammation!
