Bacteriophage biologist and enthusiast. Associate Professor at the School of Biological Sciences, Monash University.
Jeremy Barr
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- Temperate phage biology is HARD. We cant using traditional PFU plating (due to superinfection immunity), most isolates were poly-lysogens, equipment required is expensive and technically limiting, and the methods to study these phage had not been developed.
Im really excited for this work as it sets up a platform for us to study, characterise, and eventually determine what impacts temperate phages may have on the human gut microbiome. Future work may even allow us to manipulate the gut using these unique viruses.
A couple of highlights from the paper:
- We find >100 new bacteriophages, many of which had never been isolated before and we're only 'discovered' through metagenomic sequencing approaches.
