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Researcher in #platelets #cytoskeleton regulation #PTM modifications #teaching #Trailrunning #pastries #food #Paris #trips #lgbtqia+ #he #him #puglover & 🏳️‍🌈
Alex K
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Farewell party for Jean. End of an amazing PhD and the beginning of a new story in @immunothrombosis.bsky.social lab in Munich. #research #phd #postdoc #mentorship
11mo
A special day: Jean Solarz, my first PhD student, successfully defended his thesis. Proud of all the work accomplished! Thks to jury members.
We have worked for 2 years with @dianvanderwaldr.bsky.social to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis www.jthjournal.org/article/S153... #hemsky #hemesky
Bravo Jean Solarz for your presentation at the French Society of Hematology on MICAL1 @hithlabinserm1176.bsky.social #sfh #Hemsky #hemesky
Incredible trail ! 45 km, 2000 D+/2600 D- #utgc Ultra Trail du Grand Colombier, Ain
Finisher of Ecotrail of Paris, 46 km! Château de Versailles->Tour Eiffel #Ecotrail #paris #trail #trailerunning #ecotrailparis
Great collaboration with Hana Raslova and @alessandrabalduini.bsky.social teams on BSS signaling defect! Recently published. @hithlabinserm1176.bsky.social haematologica.org/article/view...
Jun 5, 2025
Excited to share that our paper is out in @natcomms.nature.com 🔗 rdcu.be/ez3Gt We uncover how MICAL1 regulates actin dynamics to enhance VWF–GPIbα binding in platelets. Big thanks to all co-authors & collaborators ! @hithlabinserm1176.bsky.social @echardlab-pasteur.bsky.social
Mar 25, 2025
Apr 4, 2025
May 25, 2025
Mar 22, 2025
Alex K
Mar 19, 2025
10mo
Plenary session at the SFH with Prof. Marie-Christine Alessi invited for a talk on phenotype/genotype in platelet disorders with Hana Raslova as moderator. #hemesky #hemsky #sfh
F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets
Nature Communications - To stop bleeding from an injured vessel, platelets adhere and form a clot despite high shear stress from the flow. Here, the authors show that platelet actin disassembly is...
rdcu.be
Alex K
Alex K
Apr 2, 2025
Alex K
Alex K
Alex K
It's all about glycans! 🍡🍢 #glycosky Our @isth.org SSC paper is now!
Alex K
Alex K
Mar 25, 2025
Société Française de Thrombose et d'Hémostase
Dianne
Huge congratulations to Dr Jean Solarz for brilliantly defending his PhD today! And to his supervisors @alexkzis.bsky.social and Frederic Adam. We are very proud of you! A big thank you to all the committee members Prof N Ajzenberg, Dr MP Gratacap, Dr G Romet-Lemonne, Dr Leon, and Dr Ho-Tin-Noe
Jun 5, 2025
Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: Communication from the ISTH SSC Subcommittee on Platelet Physiology.
Platelets contain many heterogeneous carbohydrates (glycans): often capped by sialic acid. The removal of sialic acid (desialylation) is important for platelet function and clearance, leading to novel...
www.jthjournal.org
HITh lab InsermU1176
haematologica.org
Early View | Haematologica
We have worked for 2 years with @dianvanderwaldr.bsky.social to propose a protocol for platelet desialylation, and we are excited to now share it. Communication from the ISTH SSC Platelet Physiology. - Journal of Thrombosis and Haemostasis www.jthjournal.org/article/S153... #hemsky #hemesky
Mar 25, 2025
Platelets contain many heterogeneous carbohydrates (glycans): often capped by sialic acid. The removal of sialic acid (desialylation) is important for platelet function and clearance, leading to novel...
www.jthjournal.org
Consensus protocol for platelet desialylation (β-galactose exposure) quantification using lectins by flow cytometry: Communication from the ISTH SSC Subcommittee on Platelet Physiology.
Alex K