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This concept is based on our recent work (www.researchsquare.com/article/rs-8...).
www.researchsquare.com
Intra-tumour heterogeneity (ITH) and cellular plasticity contribute to therapy resistance. Single-cell transcriptomics is the gold standard for assessing ITH, but this approach remains costly and slow...
Simple cell geometry metrics reveal cancer cell diversity and plasticity and guide combination therapy
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Chris Marine Lab