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OSMR study published! By identifying biallelic OSMR deficiency as a novel Primary Atopic Disorder, we uncover a previously unrecognized mechanism driving severe allergic disease and provide new insights into the biology of human atopy. Congratulations to an outstanding team of collaborators.
15d
Turvey Lab
New human primary atopic disorder defined: Samra and Sharma et al. show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. rupress.org/jhi/article/... #Immunology #Genetics #Atopy #IEIs @turveylab.bsky.social
16d
Journal of Human Immunity