I am excited to share the first preprint from my postdoc work! We found that ligand-receptor pairs are not static and show an antagonistic spatial localization! We show ligand is important to fine tune the amplitude of Wnt oscillations ensuring robust tissue patterning! Check out the preprint!
Virginia De Andrade
Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
