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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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A new tool for structural phylogenetics: Folddisco makes connecting structural conservation to evolutionary signal beyond the twilight zone of protein sequence similarity a tractable problem. #StrPhy
5d
Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com​​​​​​​​​​​​​​​​ 🌐 https://search.foldseek.com/folddisco
Caroline Puente-Lelievre
8d
Folddisco enables protein structural motif search in million scale databases.
www.nature.com
Structural motif search across the protein universe with Folddisco - Nature Biotechnology
Martin Steinegger 🇺🇦
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco
11mo
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Martin Steinegger 🇺🇦