AlphaFold is moving beyond single proteins to predicting complexes. Millions of interactions with strong confidence. This kind of data will help uncover how protein interactions evolve, how new functions arise, and how complex biological systems are built over time. Exciting to see where this goes!
Caroline Puente-Lelievre
AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions
π research.nvidia.com/labs/dbr/ass...
π alphafold.ebi.ac.uk