LSRF Postdoc Fellow at Princeton University | te Velthuis Lab| Interested in RNA viruses #influenza #coinfection🧬🦠 🧫🔬🌡️| Previously #biofilms #pseudomonas #phages |She/Her|🇺🇸~🇮🇳
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Writing this piece brought back eight years of joyful and transformative memories since leaving India. Those years were shaped not only by microbiology, but by visas, new cultures, and constant adaptation. The people and places along the way influenced my trajectory as much as the science.
Decoding influenza virus: From polymerase mechanisms to translational therapeutics
www.sciencedirect.com/science/arti...
Thanks to all the collaborators and my mentor @ajtevelthuis.bsky.social for his support and guidance!
Really enjoyed giving a talk at the GRC meeting on the Biology of Acute Respiratory Infection. Excellent talks and meaningful discussions all around. Until next time! 🧫🦠🫁🧬
Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...
🚨New Influenza Tool🚨
Interested in IAV mutations?
Looking for markers of mammalian adaptation?
Frustrated by converting between IAV numbering systems?
The #Flu-MutationExplorer, a new tool from @cvrbioinfo.bsky.social and @royalvetcollege.bsky.social, is here to help:
flu-gdb.cvr.gla.ac.uk
(1/n)
A wonderfully engaging essay on my favorite model bacterium, Pseudomonas aeruginosa - a genuinely compelling and highly recommended read from quorum‑sensing legend Prof. E. P. Greenberg. #biofilms #sociomicrobiology journals.asm.org/doi/10.1128/...
Ever wondered how fever helps fight flu? Our research shows that fever-like temperature tip the scales in the battle between the influenza virus and the immune system by enhancing antiviral responses and altering viral RNA dynamics. Check out the full article here:
www.science.org/doi/10.1126/...
Karishma Bisht
Ervin Fodor
Now live! Nearly all human genes contain multiple transcript isoforms - and the genes that predominantly control infection, ISGs, are no different. Using PacBio with analysis help from Yan Guo, Himadri noticed a never-before-seen transcript isoform of ISG15 that potently restricts flu 1/4
Congratulations to @karishmabisht.bsky.social with her paper on the effect of fever on influenza replication and innate immune activation! www.science.org/doi/10.1126/...