//
sign in
Post
by @danabra.mov
PostEmbed
by @danabra.mov
Record
by @jimpick.com
Record
by @atsui.org
+ new component
Post
Paquet lab addresses iPSC limitation: new line with endogenous P301L/S320F 4R tau develops age-related tauopathy phenotypes stem cells typically fail to model. Platform shows pathological tau aggregation for more precise tauopathy research & drug screening www.science.org/doi/10.1126/...
www.science.org
A human iPSC–derived tauopathy model endogenously recapitulates late-stage pathology and enables translational applications.
A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology
2mo
Gan Lab