PanNDA leverages deep proteomics of 2,279 human brain samples in AD, LBD, FTD-TDP-43, PSP, VD, & PD to reveal shared disease mechanisms, spotlighting GPNMB (microglial/lysosomal activation) & NPTX2 (synaptic regulation). Paper: www.cell.com/cell/fulltex.... Data: penglab.shinyapps.io/pannda.
A pan-neurodegeneration atlas built from multilayer, deep proteomics of 2,279 brain
samples across 6 major diseases integrates whole proteome, detergent-insoluble proteome,
and posttranslational modif...
