Just out: Unlocking Lewis acid–free metalation of O–nucleophiles in HFIP
Communications Chemistry, Published online: 02 June 2026; doi:10.1038/s42004-026-02079-3Allylsilanes are typically used in C–C bond formation, but their potential as silylating agents for Si–O bond creation has been limited by the need for acid catalysis. Here, the authors introduce an acid-free method using hexafluoroisopropanol to efficiently convert alcohols and silanols into silyl ethers, siloxanes, and borasiloxanes.
