Just out: Heavy water labeling reveals metabolic flexibility of amino acid and polyamine pathways in mammalian cells
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Communications Chemistry, Published online: 29 May 2026; doi:10.1038/s42004-026-02081-9Amino acid and polyamine metabolism are crucial for cellular functions, yet its pathway usage varies with context and compensatory mechanisms. Here, the authors employ short-term, low-dose heavy water labeling to trace these metabolic processes, revealing tissue-specific biosynthetic capacities.
