Exploring the molecular biology of #ubiquitin and #VCPp97 -mediated stress responses in cells, #proteostasis, #lysophagy, #autophagy, #DNArepair.
http://udue.de/qmTDR
Hemmo Meyer Lab
Meeting new and old friends at the JPS conference in Kyoto, Japan. Presented our newest data on the #Lysosome Damage Response. #ATXN3 Thanks to the organizers.
Thrilled to be hosting Brenda Schulman, @aakritijain.bsky.social, @crismayorruiz.bsky.social @davidbalchin.bsky.social, @hemmo-lab.bsky.social, Ian Ganley, @kirsteinlab.bsky.social, Juliette Fedry, @elliottlab.bsky.social & @plantophagy.bsky.social - BIG THANKS for accepting the invitation π
Excellent talk by our @unidue-zmb.bsky.social colleague Pinki Galhot from @hemmo-lab.bsky.social @imprs-lm.bsky.social π #MK2026 @gbmev.bsky.social
Hemmo Meyer Lab
Great #ubfriends2026 meeting in Vienna. Presented our data on FAF1/2 mediated substrate loading onto VCP/p97. Fantastic talks, discussions and hospitality. Big thank you to the organizers! #ubiquitin
Finally celebrating Matthiβs paper publication on p97βs accessory adapters. Great job. doi.org/10.1126/scia...
Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now.
rdcu.be/firGK
The Meyer lab Xmas dinner once again with traditional German skittle competition. We won! π³
VCP/p97βs accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now:
Science Advances www.science.org/doi/10.1126/...
Fantastic and productive meeting with the labs of Tamotsu Yoshimori, Shuhei Nakamura, Akiko Kuma at #Osaka University. Discussing perspectives of #microautophagy in th #lysosome regeneration after damage. Thanks so much for hosting me.
Fantastic #autophagy meeting on the Oslo Fjord. Great talks and plenty of time and activities for discussion. Thanks to Anne, Ivan, Sharon and the other organizers for a great event.
SFB Targeted Protein Degradation
Hellerschmied Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
Hemmo Meyer Lab
A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.