🚨 New in JMCC! The GWAS-identified CAD risk gene and transcription factor PRDM16 is a key regulator of VSMC homeostasis, promoting proliferation and neointima formation by repressing Tgfb2 expression.
www.jmcc-online.com/article/S002...
Vascular smooth muscle cells (VSMCs) are the primary contractile component of blood vessels and can undergo phenotypic switching from a contractile to a synthetic phenotype in vascular diseases such…
