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Great to see our work published in CELL Using patient-derived iPSCs and organoids, we identified PDE5 inhibitors as candidates for Leigh syndrome Early patient data support clinical translation. Congrats to the team, especially Alessandro Prigione 🔗 tinyurl.com/2sbfk463 #StemCells #Mitochondria
2mo
Excited to share that our work on CleanFinder is published in Trends in Biotechnology! 🎉 Analyzing complex allele mixtures across editing modalities and sequencing platforms is a major bottleneck. We developed CleanFinder to solve this. Read it here: www.sciencedirect.com/science/arti...
RossiLab
21d
www.sciencedirect.com
Genome editing often generates complex mixtures of alleles rather than single, predefined outcomes. Resolving these heterogeneous edits across diverse…
CleanFinder: a scalable framework for comprehensive genome editing analysis
RossiLab
Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leig…
tinyurl.com
Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy