"metabolic-cytoskeletal axis that determines cellular polarity or a/symmetry prior to the onset of cell division. This suggests that polarity loss during cytokine-driven culture is a regulated feature of early cellular adaptation, rather than an inevitable consequence of cell-cycle entry"
Ben Doughty
Spatiotemporal Proteome Remodeling Directs Human Hematopoietic Stem Cells via a Metabolic-Cytoskeletal Axis https://www.biorxiv.org/content/10.64898/2026.06.08.728414v1
