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#JournalClub🚨 Stephenson-Gussinye & Furlan-Magaril explore how 3D genome reorganization explains why only some variants drive gene expression changes in cancer 📖👇
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In this Journal Club, Stephenson-Gussinye and Furlan-Magaril discuss a study exploring how structural variants reshape three-dimensional genome architecture in cancer, explaining why only a subset lead to functional changes in gene expression.
Structural variants disrupt chromatin architecture - Nature Reviews Cancer
Nature Reviews Cancer