This was a fun project led by the hugely talented postdoc Rachana Somaiya and graduate student Matthew Po together in collaboration with @mfeller.bsky.social !
Karthik Shekhar
New preprint! A wonderful collaboration of our @FellerMarla lab with Matthew Po, and @shekharlab. Here, we dive into the impact of spontaneous activity on the transcriptome of retinal ganglion cells (RGCs), the sole output neurons of the retina. www.biorxiv.org/content/10.1...
In the early stages of retinal development, a form of correlated activity known as retinal waves causes periodic depolarizations of immature retinal ganglion cells (RGCs). Retinal waves are crucial fo...