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In vitro reconstruction study providing cool new insights into "AT-less" PKS. Internal KSo domains for non-elongating modules. #natprod www.nature.com/articles/s41...
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Decarboxylative condensation is essential for polyketide and fatty acid biosynthesis, yet the mechanism underlying nonelongating modules without this step remains elusive. Here the authors report a co...
www.nature.com
Condensation-independent intramodular translocation mechanism of the trans-AT polyketide synthase assembly line - Nature Chemical Biology
Brian O. Bachmann