PI Virologist & Wellcome Trust/Royal Society Sir Henry Dale fellow studying RNA viruses at the University of Cambridge
Valeria Lulla
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#JGV is recruiting a new Editor for positive-strand RNA viruses. If you’re interested in contributing to the journal and the field, I’d be happy to share my editorial experience - please get in touch!
Congratulations to David Noyvert on acing his PhD viva! Many thanks to the excellent examiners @markohyvonen.bsky.social and Lidia Vasilieva!
🚨 New paper from the lab! 🚀 We explore “The dynamics and strategy of RNA replication in astroviruses”, now out in NAR Molecular Medicine. Many thanks to all co-authors and congratulations to David Noyvert on his first first-author paper🎉
doi.org/10.1093/narm...
On the first day of Christmas, a virus gave to me...
📢 5 days left to apply for a PhD studentship in molecular virology in my lab: www.findaphd.com/phds/project...
📢How do astroviruses replicate their RNA genome? Led by a talented PhD student in the lab, David Noyvert, this story identifies novel (-)sgRNA species, shows terminal features of viral RNAs, and uncovers the secret life of RNA replication dynamics and packaging!
www.biorxiv.org/content/10.6...
🚨 New paper from the lab! 🚀 We explore flexibility and modulation of IRES-dependent translation in enterovirus genomes through upstream ORFs. Many thanks to all co-authors from the @campathology.bsky.social, CIMR and Cambridge Stem Cell Institute!
dx.plos.org/10.1371/jour...
📢Astrovirus polyprotein processing is finally uncovered - these viruses use peculiar dual cleavage sites around their protease! Led by a talented PhD student, David Noyvert, this work provides a map of astrovirus genomes. Great collaboration with @emmottlab.bsky.social @leandroxneves.bsky.social
Abstract. Astroviruses are positive-sense single-stranded RNA viruses that cause significant disease across avian and mammalian hosts, yet their replicatio
We did a thing:
Scientists find a new way coronaviruses can get into human cells www.cam.ac.uk/research/new...
How does fever work?
Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.
This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵
www.science.org/doi/10.1126/...
Author summary Enteroviruses cause over a billion infections annually, leading to serious conditions such as hand, foot, and mouth disease and viral meningitis. While these viruses are known to encode...
dx.plos.org
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...