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PI Virologist & Wellcome Trust/Royal Society Sir Henry Dale fellow studying RNA viruses at the University of Cambridge
Valeria Lulla









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#JGV is recruiting a new Editor for positive-strand RNA viruses. If you’re interested in contributing to the journal and the field, I’d be happy to share my editorial experience - please get in touch!
Congratulations to David Noyvert on acing his PhD viva! Many thanks to the excellent examiners @markohyvonen.bsky.social and Lidia Vasilieva!
🚨 New paper from the lab! 🚀 We explore “The dynamics and strategy of RNA replication in astroviruses”, now out in NAR Molecular Medicine. Many thanks to all co-authors and congratulations to David Noyvert on his first first-author paper🎉 doi.org/10.1093/narm...
3mo
3mo
On the first day of Christmas, a virus gave to me...
1mo
📢 5 days left to apply for a PhD studentship in molecular virology in my lab: www.findaphd.com/phds/project...
📢How do astroviruses replicate their RNA genome? Led by a talented PhD student in the lab, David Noyvert, this story identifies novel (-)sgRNA species, shows terminal features of viral RNAs, and uncovers the secret life of RNA replication dynamics and packaging! www.biorxiv.org/content/10.6...
🚨 New paper from the lab! 🚀 We explore flexibility and modulation of IRES-dependent translation in enterovirus genomes through upstream ORFs. Many thanks to all co-authors from the @campathology.bsky.social, CIMR and Cambridge Stem Cell Institute! dx.plos.org/10.1371/jour...
📢Astrovirus polyprotein processing is finally uncovered - these viruses use peculiar dual cleavage sites around their protease! Led by a talented PhD student, David Noyvert, this work provides a map of astrovirus genomes. Great collaboration with @emmottlab.bsky.social @leandroxneves.bsky.social
6mo
6mo
4mo
4mo
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Abstract. Astroviruses are positive-sense single-stranded RNA viruses that cause significant disease across avian and mammalian hosts, yet their replicatio
doi.org
The dynamics and strategy of RNA replication in astroviruses
Valeria Lulla
Valeria Lulla
We did a thing: Scientists find a new way coronaviruses can get into human cells www.cam.ac.uk/research/new...
How does fever work? Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence. This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵 www.science.org/doi/10.1126/...
Valeria Lulla
1mo
6mo
Valeria Lulla
Valeria Lulla
Valeria Lulla
Valeria Lulla
Ed Hutchinson
Sam J Wilson
Stephen Graham's Lab
Flexibility and modulation of translation initiation in enterovirus genomes
Author summary Enteroviruses cause over a billion infections annually, leading to serious conditions such as hand, foot, and mouth disease and viral meningitis. While these viruses are known to encode...
dx.plos.org
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...
www.biorxiv.org
Viral protease-mediated polyprotein processing in human astroviruses