New Preprint! When one enhancer allele changes another's regulatory output, is that bad? We found it could be a feature — interallelic cis-regulatory dominance buffers outputs AND enables evolutionary innovation. Two for one!
Led by @ottilie.bsky.social from @embl.org
doi: doi.org/10.64898/202...
🚨3 days left❗to submit your abstract for the Society for Developmental Biology Annual Meeting 2026 in Las Vegas! 🎰🃏 Don’t miss your chance to share your science, connect with the dev bio community, and join us in Vegas ➡️ www.sdbonline.org/2026mtg_abst... ✨ #SDB2026 #DevBio #DevelopmentalBiology
Everyone from the Global South moving to the Global North for a postdoc should hear this advice:
Delighted to share our lab's latest (w/ inimitable @genophoria.bsky.social) in final form at @nature.com. Enormous lift by Sean Wang, @palindromephd.bsky.social & @martyyang.bsky.social to address extensive & constructive reviewer comments & see this through. (1/n) www.nature.com/articles/s41...
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬
Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles
By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪
🧵👇