This is especially true for soft-money positions (ask me how I know): can't support 75-100% salary on 3 grants if 2 of them are ≤5% MPI R21s. R03? Fuhgeddaboudit.
Roby Bhattacharyya
Limiting the number of NIH RPG a person can serve as PI does two things, ~immediately. It kills any interest in MPI proposals that remained after the 6-proposal limit. It kills interest in R03 and R21 proposals.