Are we born as a blank slate, or with a neural “operating system”?
We show hippocampal neurons self-organize into memory-like networks in a dish.
We also introduce IncStim, a compact, all-optical sys. for closed-loop act. imaging/manipulation inside an incubator.
www.biorxiv.org/content/10.6...
A milestone worth reflecting on - 1000 citations for our cleared tissue light sheet paper - the COLM.
Gratifying that core ideas have stood the test of time and are broadly adopted:
Cuvette-based sample mounting;
Virtual slit effect with rolling shutter CMOS;
and Linear adaptive offset correction!
Raju Tomer
Love this!! I don’t think I’ve ever seen anything like this before -- high-res light sheet microscopes designated for use by individual researchers in one lab!! Fantastic to see real-world impact emerging, starting with Bianca’s lab at JLG, Columbia!
The key figure:
HySIL / pLSM-SCOPE / SLICE work out now in Nature Biotechnology (open article)!
Our digital times :-)
Sharing new work from us+collaborators. We take a step toward making organ-scale, subcellular 3D imaging as scalable & affordable as next-gen sequencing, to eventually fuel next-gen of AI-foundational models of tissues, organs. www.biorxiv.org/content/10.1...
Videos: www.youtube.com/playlist?lis...
Raju Tomer
We’re proud to work with Dr. Tomer & his team at Columbia University to bring SLICE to life, a compact, affordable light-sheet microscope making 3D imaging more accessible worldwide.
📖 magazine.columbia.edu/article/3d-i...
@rtomer.bsky.social @columbiauniversity.bsky.social
#SLICE #lightsheet
Raju Tomer
Raju Tomer
Raju Tomer
Raju Tomer
Eric Topol
@rtomer.bsky.social :
Pizza time at AQLM!
@aqlm.bsky.social !
We had to join the trend.
Introducing: Jack Glaser, Founder and President of MBF Bioscience —now an action figure. Complete with microscope, field journal, and trusty lab dog. 🧠🐕
In science, there are no small people—just big ideas.
#ScienceMatters #STEM #Microscopy
MBF Bioscience
MBF Bioscience
Hybrid solid−liquid optics enable scalable, high-resolution light-sheet microscopy across diverse immersion media - @rtomer.bsky.social @columbiauniversity.bsky.social go.nature.com/4xdDkQR
Hybrid solid–liquid optics improve light-sheet imaging of intact biological samples.
Three-dimensional neuronal cultures, such as brain organoids, have proven effective for in vitro modeling of brain development and disease. However, it remains unclear whether these systems can intrin...
✨ Exciting news!
SLICE™, our award-winning light sheet microscope, is now up and running at the Marlin Lab at Columbia University @columbiauniversity.bsky.social, ready to power advanced 3D imaging and accelerate discovery.
Here’s to more breakthroughs ahead! 🚀🔬
#3DImaging #ResearchInnovation
MBF Bioscience
Columbia researchers have developed a powerful new microscope that could enable more scientists around the world to conduct cutting-edge biomedical research.
