Head of the Antigen Evolution and Design lab at Institut Pasteur 🇫🇷
💻🦠🏳️🌈
Spyros Lytras
A very busy but exciting first week at @pasteur.fr !!
Got a nice empty office that will hopefully start filling up soon! 😁😁
I've built some initial Nextstrain phylogenies of the Andes Hantavirus variant, which include the sequence generated by HUG & UniZurich, Switzerland.
Please interpret with caution.
By segment:
S: nextstrain.org/groups/hodcr...
M: nextstrain.org/groups/hodcr...
L: nextstrain.org/groups/hodcr...
People have got to wake up to how bad the situation in US science is right now
New online! Concepts of RNA virus evolution for the design of better antiviral countermeasures
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
📣📣Very pleased to welcome @spyroslytras.bsky.social to our department @ipdbsc.bsky.social @pasteuredu.bsky.social
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Spyros Lytras
Long story short, looks like a likely spillover from the O. longicaudatus rodent Argentina/Chile natural reservoir from a clade of Andes hantavirus that frequently infects humans.
alignments and trees for other to pick up the analysis available in the link above!
Super quick sequencing from the Swiss team!!
I found some time to do a quick phylo analysis posted here:
virological.org/t/complete-s...
#hantavirus #ANDV
some updates and small corrections on the hantavirus phylogeny below:
virological.org/t/complete-s...
the cruise ship virus is from ANDV Clade 3 (see Fig2A journals.asm.org/doi/10.1128/...)
Clade 3 has confirmed human cases, Clade 2 has confirmed H2H, safe to assume both can H2H
#ANDV
Nextstrain #ANDV trees updated with a few improvements:
- 2 outbreaks marked
- host scientific/common name added
- province now visible on map
- date colouring added
Here's a quick tour of how to change colours, geography & names!
Links to trees here (scroll down):
nextstrain.org/groups/hodcr...