🚨New paper alert🚨
We built a fully standardized, integrated hardware and software solution for real-time welfare monitoring in mice. We used it to look at pain management after brain surgery.
Not much has changed from the preprint (see below).
Brief: hold back on opioids!
doi.org/10.1038/s416...
The authors present the GrimACE, an automated cage-side system that uses computer vision to score mouse pain and behavior. The tool, which detects postsurgery pain and analgesic effects, enables repea...
How much analgesia is needed to manage pain levels in mice after brain surgeries?
A single dose of meloxicam seems to be enough. Even the addition of opioids cannot provide a clear benefit. (in line with recent work from others, see cites in our preprint): www.biorxiv.org/content/10.1...
Pain and welfare monitoring is essential for ethical animal testing, but current cage-side assessments are qualitative and subjective. Here we present the GrimACE, the first fully standardised and aut...
