New preprint 🚨🧠🔬
@sophiepeterson.bsky.social + @margole.bsky.social dissect the roles of 2 major OFC subcortical pathways in context-dependent reward prediction.
TLDR:
OFC→CDS: critical for hierarchical gating of predictions.
OFC→MDT: more modest role, possibly limiting non-hierarchical predictions
Ron Keiflin
Orbitofrontal circuits for context-gated reward predictions https://www.biorxiv.org/content/10.64898/2026.03.05.709962v1
