You might be able to identify potential “non-responders” and exclude them from entry but this is often quite difficult. You can’t exclude them from analysis if included in the trial.
However the NR concept is fraught with dangers.
errorstatistics.com/2014/07/26/s...
Stephen Senn Head, Methodology and Statistics Group Competence Center for Methodology and Statistics (CCMS) Luxembourg Responder despondency: myths of personalized medicine The road to drug develop…
