Excited to share that our new open access review is out today: “Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities.” This work was led by Amy Beaudin, a PhD student in the lab, who did an excellent job synthesizing a rapidly evolving field.
Abstract. Intrinsic and adaptive resistance to therapy remain major barriers to effective cancer treatment. Diverse resistance mechanisms, including epithelial-mesenchymal transition, enhanced toleran...