Excited to engineer a synthetic cell from scratch with lipid vesicles and DNA/RNA origami-based molecular hardware. Professor @ZMBHh @UniHeidelberg
Kerstin Göpfrich
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We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems - h/t @kgoepfrich.bsky.social
Still time to apply until January, 19th!
Welcome, Dana!
Recent highlights:
Received seed funding from the SynGen Center to explore synthetic genomes in bottom-up synthetic biology. 🚀
The first work of my PhD is now published:
onlinelibrary.wiley.com/doi/full/10....
Huge thanks to Franziska Gießler, Tobias Abele, Stefan Maurer, and @kgoepfrich.bsky.social
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a Tenure Track Professors...
www.nature.com
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are upt...
Ribozymes enable sequence-encoded turnover of RNA droplet material, resulting in transiently active droplets that selectively segregate based on their genotype. This establishes a direct link between...
Next up, the great Kerstin Göpfrich @kgoepfrich.bsky.social @zmbh.uni-heidelberg.de on her long-term vision of synthetic cells, and very concrete approaches using RNA origami.
#gfv2026
Is it possible to engineer new cellular life from the bottom up?
The Göpfrich group @kgoepfrich.bsky.social @mpi-mr.bsky.social have designed an RNA origami nanotube 🟡 to mimic the cytoskeleton:
www.nature.com/articles/s41...
It was a fun challenge to animate T7 RNA polymerase 🔵
#blender #b3d
We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
Video
Happy to share our latest work in collaboration with IBEC. Congratulations to recent PhD graduate and lead author @towalther.bsky.social!
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a Tenure Track Professors...
New to RNA design? Please try pyFuRNAce! Looking forward to your feedback 🧬
Curious about RNA, aptamers, lipid membranes, molecular dynamics simulations, synthetic cells - and how these topics come together? Join @floppleton.bsky.social's talk in the unano webinar blogs.ed.ac.uk/unanowebinars
Kerstin Göpfrich
Kerstin Göpfrich
[Meet our doctoral candidates 🫧]
Dana Venkert is our DC working at the Heidelberg University under the supervision of @kgoepfrich.bsky.social.
Dana, who completed her M.Sc. in Molecular, Cellular, and Systemic Neuroscience at Tel Aviv University, will now explore the RNA design world in SigSynCell
Kerstin Göpfrich
Kerstin Göpfrich
Matthew Clark
GfV - Gesellschaft für Virologie
SigSynCell MSCA DN
New paper in Advanced Materials! We present DNA hydrogel microparticles for 3D tissue engineering, showing programmable material properties and cell-material interactions! Special thanks to Eleni Dalaka
@gflaesch.bsky.social @kgoepfrich.bsky.social @xaviertrepat.bsky.social
doi.org/10.1002/adma...
Tobias Walther
PyFuRNAce is an intuitive browser-based RNA design tool.
@monari-luca.bsky.social @kgoepfrich.bsky.social @uniheidelberg.bsky.social realized the largest cotranscriptionally folded RNA nanostructures to date. #BiotechNatureComms
www.nature.com/articles/s41...
RNA nanotechnology creates structural and functional RNA architectures for biomedicine, synthetic biology and beyond. Here, the authors introduce pyFuRNAce, an intuitive browser-based RNA design tool....
